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XX.c

XX - Vasculitis

Vascultis (pulmonary, extrathoracic or systemic)-ANCA status unknown or negative)

Last update 23/07/2021

Can be granulomatous in nature (PMID 34237323). Older literature does not mention ANCA status (See under Xs). Can involve the lung, deep-seated organs (liver, kidney), viscerae, brain, extremities and/or skin or be diffuse (polyangiitis) clinically mimicking granulomatosis with polyangiitis (formerly known as Wegener's). See also under IIId and VId

Causative drugs

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic