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The Drug-Induced Cardiotoxicity Website and App

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XXXIII.n

Path: Foreign body embolism, microangiopathy, vasculopathy

Publications

Mbuvah F, Venur VA, Kistangari G

The clinical picture: an intravenous drug user with persistent dyspnea and lung infiltrates.

Cleveland Clinic journal of medicine. 2014;81(4):223-4

Leslie KO, Gruden JF, Parish JM, Scholand MB

Transbronchial biopsy interpretation in the patient with diffuse parenchymal lung disease.

Archives of pathology & laboratory medicine. 2007;131(3):407-23

WENDT VE, PURO HE, SHAPIRO J, MATHEWS W, WOLF PL

ANGIOTHROMBOTIC PULMONARY HYPERTENSION IN ADDICTS. "BLUE VELVET" ADDICTION.

JAMA. 1964;188:755-7

Hopkins GB

Pulmonary angiothrombotic granulomatosis in drug offenders.

JAMA. 1972;221(8):909-11

Feigin DS

Talc: understanding its manifestations in the chest.

AJR. American journal of roentgenology. 1986;146(2):295-301