The Drug-Induced Cardiotoxicity Website and App

BCG therapy (topical instillations in the urinary bladder)

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XXI.a

Lymphadenopathy (intrathoracic)

Publications

Mehta AR, Mehta PR, Mehta RL

A cough conundrum in a patient with a previous history of BCG immunotherapy for bladder cancer.

BMJ case reports. 2012;2012

Chang H, Klein JS, Norotsky M, Cooper K

Granulomatous chest disease following intravesical bacillus Calmette-Guerin immunotherapy.

Journal of thoracic imaging. 2004;19(1):60-2