XI - Pulmonary vasculopathies
Last update 17/06/2026
De novo or superipmosed on a background of preexisting PAH. Range from mild to catastrophic and fatal. May result from acute pulmonary vasoconstriction, extensive microembolism, or rebound vasoconstriction upon brisk withdrawal of pulmonary vasodilator therapy. See also under acute pulmonary vasoconstriction VIL
Frequency - Incidence
Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
