The Drug-Induced Cardiotoxicity Website and App

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XXIV.o

A mass or masses

Publications

Carvalho JG, Fernandes C, França M

Organizing pneumonia secondary to amiodarone treatment.

Heliyon. 2022;8(9):e10630

Ruangchira-Urai R, Colby TV, Klein J, Nielsen GP, Kradin RL, Mark EJ

Nodular amiodarone lung disease.

The American journal of surgical pathology. 2008;32(11):1654-60

Jarand J, Lee A, Leigh R

Amiodaronoma: an unusual form of amiodarone-induced pulmonary toxicity.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. 2007;176(10):1411-3

Arnon R, Raz I, Chajek-Shaul T, Berkman N, Fields S, Bar-On H

Amiodarone pulmonary toxicity presenting as a solitary lung mass.

Chest. 1988;93(2):425-7