The Drug-Induced Cardiotoxicity Website and App

XXIV.s

XXIV - Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

Lung nodule or nodules

Last update 11/09/2026

(Fr: nodule unique ou multiples). See also under Iq. Drug-induced lung nodule(s) may correspond to areas of organising pneumonia, granuloma, vasculitis, fibrosis, amiodarone pulmonary toxicity, sterile necrosis, endogenous or exogenous lipoid pneumonia or Pyoderma gangrenosum. In RA, rheumatoid nodules may exhibit changes under therapy with DMARDs (see under Ip). Most nodules in the immunodepressed are due to an infection (PMID 24895041). Particulars of RA patients under Iq

Causative drugs

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic