The Drug-Induced Cardiotoxicity Website and App

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

II.b

Atrial fibrillation

Publications

Addison D, Quartermaine C, Brammer JE

Atrial Fibrillation With Modern Cancer Treatment: More Common Than We Think.

JACC. CardioOncology. 2023;5(2):227-229

Ahmad J, Thurlapati A, Thotamgari S, Grewal US, Sheth AR, Gupta D, Beedupalli K, Dominic P

Anti-cancer Drugs Associated Atrial Fibrillation-An Analysis of Real-World Pharmacovigilance Data.

Frontiers in cardiovascular medicine. 2022;9:739044