The Drug-Induced Cardiotoxicity Website and App

XXIV.z

XXIV - Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

Exogenous lipoid pneumonia (subacute, acute)

Last update 11/09/2026

(Fr: PnP lipidique exogene). Subacute, chronic or, less often, acute causing ARF (PMID 27372295). Consists in the spread and aspiration of mineral oil or fluid hydrocarbons in the lower respiratory tract. Stainable lipids can be evidenced in sputum, BAL macrophage, BAL flluid and lung tissue. Hiatal hernia and achalasia may be risk factors for ELP (PMID 13834170). See also under patterns Iae, Iag and XVo

Causative drugs

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic