The Drug-Induced Cardiotoxicity Website and App
Frequency - Incidence
Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Gross or microscopic bleeding/hemorrhage in lung tissue
Publications
Villeneuve T, Prevot G, Le Borgne A, Colombat M, Collot S, Ruiz S, Lanot T, Brouchet L, Rabeau A, Noel-Savina E, Didier A
Diffuse alveolar haemorrhage secondary to e-cigarette "vaping" associated lung injury (EVALI) in a young European consumer.
The European respiratory journal. 2020;56(1)
Acute Respiratory Failure Associated With Vaping.
Chest. 2020;157(3):e63-e68