The Drug-Induced Cardiotoxicity Website and App

XXXIV.e

XXXIV - Infections

Tuberculosis (pulmonary, pulmonary, extrapulmonary or disseminated). Reactivation or de novo

Last update 27/06/2021

This includes classic presentations of pulmonary TB and miliary tuberculosis which can be severe or fatal. A search for extrapulmonary TB is indicated in all cases. Drug-associated TB can occur via reactivation of prior latent TB or it is newly acquired. TB can be pulmonary, thoracic, extrathoracic or disseminated. See also under XVIIf, XVIIh, XVIIi

Causative drugs

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic