The Drug-Induced Cardiotoxicity Website and App

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XXXIII.y

Path: Acute fibrinous organizing pneumonia (AFOP-pattern)

Publications

Naraoka T, Sumi T, Keira Y, Nakata H, Chiba H

Epirubicin and Cyclophosphamide-induced Acute Fibrinous and Organizing Pneumonia.

American journal of respiratory and critical care medicine. 2021;204(8):e92-e93

Gomes R, Padrão E, Dabó H, Soares Pires F, Mota P, Melo N, Jesus JM, Cunha R, Guimarães S, Souto Moura C, Morais A

Acute fibrinous and organizing pneumonia: A report of 13 cases in a tertiary university hospital.

Medicine. 2016;95(27):e4073