The Drug-Induced Cardiotoxicity Website and App

XXIV.n

XXIV - Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

Subclinical pulmonary infiltrates/ILD

Last update 11/09/2026

(Fr. atteinte infraclinique). Interstitial or alveolar opacities detected incidentally on HRCT or if the BAL shows increased lymphocytes, neutrophils or eosinophils. PFTs typically yield normal results. See also under Iv

Causative drugs

8

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

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