XXXVIII - Miscellaneous - Varia
Last update 17/06/2026
Antiphospholipid- or antisynthetase Ab syndrome (APS-APLS). Including circulating lupus anticoagulant, anticardiolipin Ab and anti-beta2glycoprotein Ab. Possible complications include VTE, pulmonary thromboembolism, pulmonary hypertension, DAH and ILD
Frequency - Incidence
Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
