The Drug-Induced Cardiotoxicity Website and App

E-cigarette - E-vaporizers - ENDS - Vaping - Dabbing

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XIV.f

Pneumothorax

Publications

Manchen PJ, Larsen BT, Smith ML, Tazelaar HD, Butt YM

EVALI and Beyond: An Update on the Spectrum of Vaping-Associated Lung Pathology.

The American journal of surgical pathology. 2026

Borchert DH, Kelm H, Morean M, Tannapfel A

Reporting of pneumothorax in association with vaping devices and electronic cigarettes.

BMJ case reports. 2021;14(12)

Bonilla A, Blair AJ, Alamro SM, Ward RA, Feldman MB, Dutko RA, Karagounis TK, Johnson AL, Folch EE, Vyas JM

Recurrent spontaneous pneumothoraces and vaping in an 18-year-old man: a case report and review of the literature.

Journal of medical case reports. 2019;13(1):283