The Drug-Induced Cardiotoxicity Website and App

I. Myocardial dysfunction - Heart failure

I.e Acute respiratory or cardiopulmonary failure

II. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

II.l Cardiac- cardiorespiratory/pulmonary arrest

VI. Cardiomyopathy

VI.a Cardiomyopathy (acute, subacute, chronic)

XXII. Acute respiratory/cardiorespiratory failure

XXII.e Respiratory failure from ventilatory depression (due to neuromuscular blockade/paralysis)

XXII. Acute respiratory/cardiorespiratory failure

XXII.f Chest wall muscle rigidity - Stiff/wooden chest

XXVIII. Large airway involvement including UAO

XXVIII.f Laryngospasm (a.k.a. laryngismus)

XXXV. Disordered breathing during sleep

XXXV.b Disordered breathing pattern incl. Cheyne-Stokes respiration

XXXVIII. Miscellaneous - Varia

XXXVIII.n Hiccup

XXII. Acute respiratory/cardiorespiratory failure

XXII.a Respiratory distress or failure, not otherwise specified

XXVIII. Large airway involvement including UAO

XXVIII.d Vocal cord dysfunction, adduction, closure, injury

XXXVIII. Miscellaneous - Varia

XXXVIII.a Upper airway obstruction other than angioedema or hematoma

II. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

II.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

III. Myocardial ischemia - Coronary artery disease

III.a Coronary artery disease (acute) - Myocardial ischemia/infarction

X. Pulmonary edema - ALI/ARDS

X.b Pulmonary edema, noncardiogenic (NCPE)

XXVIII. Large airway involvement including UAO

XXVIII.g Thermal (burns, frostbite), chemical or caustic injury on the face, mouth, tongue, pharynx or upper airway

XXIX. Small airway involvement

XXIX.a Bronchospasm - Wheezing - Asthma

XII. Pericardial involvement

XII.g Pleural/pericardial effusion, ANA positive (DI lupus)

XIII. Thrombosis - Embolism

XIII.a Pulmonary embolism - Venous thrombosis/thromboembolism

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

XXVI. Neuromuscular dysfunction

XXVI.e Respiratory dyskinesia

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.b Lupus - Lupus syndrome (see also Vd)

XXXVIII. Miscellaneous - Varia

XXXVIII.c Antiphospholipid antibodies w/wo the APL syndrome

XIV. Pleural involvement

XIV.d Eosinophilic pleural effusion

XIX. Angioedema

XIX.b Visceral angioedema (can cause relapsing abdominal pain)

XXVIII. Large airway involvement including UAO

XXVIII.a Angioedema (may cause UAO, asphyxia and death)

XXVIII. Large airway involvement including UAO

XXVIII.i Tongue involvement (edema, glossitis, hematoma)

XXIX. Small airway involvement

XXIX.d Cough (lone)

I. Myocardial dysfunction - Heart failure

I.d Cardiovascular collapse - Cardiogenic shock - Hypotension

II. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

II.e Bradycardia

X. Pulmonary edema - ALI/ARDS

X.h Negative pressure pulmonary edema (NPPE)

XXIX. Small airway involvement

XXIX.c Severe or catastrophic bronchospasm or asthma attack (can be fatal)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.f Anaphylaxis-Anaphylactoid reaction (can be fatal)