The Drug-Induced Cardiotoxicity Website and App

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XXXVIII.c

Antiphospholipid antibodies w/wo the APL syndrome

Publications

Iyer HV, Moudgil H, Newman P, Srinivasan KS

Chlorpromazine-associated antiphospholipid antibody syndrome.

The Annals of pharmacotherapy. 2007;41(3):528

Matsukawa Y, Satoh M, Itoh T, Nishinarita S, Horie T, Abe K, Takahashi A, Kojima T

Plasmapheresis for a schizophrenic patient with drug-induced lupus anti-coagulant.

The Journal of international medical research. 1996;24(1):147-50