The Drug-Induced Cardiotoxicity Website and App

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XXXVI.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Dichtwald S, Meyer A, Miller Y, Mirit L

Sugammadex-Induced Anaphylactic Shock Reversed With Short-Term Continuous Veno-Venous Hemodiafiltration: A Case Report.

A&A practice. 2023;17(11):e01725

Sadleir PH, Russell T, Clarke RC, Maycock E, Platt PR

Intraoperative anaphylaxis to sugammadex and a protocol for intradermal skin testing.

Anaesthesia and intensive care. 2014;42(1):93-6