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The Drug-Induced Cardiotoxicity Website and App

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XXIX.d

Cough (lone)

Publications

Dicpinigaitis P, Satia I, Ferguson N

Falsely Accused? Insufficient Evidence to Conclude that Sitagliptin is a Cause of Chronic Cough.

Lung. 2020;198(2):271-273

Tseng DS, Kwong J, Rezvani F, Coates AO

Angiotensin-converting enzyme-related cough among Chinese-Americans.

The American journal of medicine. 2010;123(2):183.e11-5

Noble TA, Murray KM

Lisinopril: a nonsulfhydryl angiotensin-converting enzyme inhibitor.

Clinical pharmacy. 1988;7(9):659-69

Just PM

The positive association of cough with angiotensin-converting enzyme inhibitors.

Pharmacotherapy. 1989;9(2):82-7