The Drug-Induced Cardiotoxicity Website and App

X.e

X - Pulmonary edema - ALI/ARDS

Overload pulmonary edema (including posttransfusional (TACO))

Last update 17/06/2026

(Fr: OAP de surcharge). Circulatory overload pulmonary edema occurs when the rate or amount of fluid infused is above what the circulatory system can accomodate. The variant after blood transfusion is named TACO for transfusion-associated circulatory overload.

Causative drugs

3

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic