Back to drug

The Drug-Induced Cardiotoxicity Website and App

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.b

Pulmonary edema, noncardiogenic (NCPE)

The respective role of tocolytic agents, underlying cardiac disease, fluid overload, and preeclampsia must be evaluated

Publications

Hamel H, Bonniaud P, Baudouin N, Spagnolo G, Sagot P, Camus P

[Pulmonary edema and tocolysis with beta-agonists].

Revue des maladies respiratoires. 2002;19(2 Pt1):241-4

Lamont RF

The pathophysiology of pulmonary oedema with the use of beta-agonists.

BJOG : an international journal of obstetrics and gynaecology. 2000;107(4):439-44

Clesham GJ

Beta adrenergic agonists and pulmonary oedema in preterm labour.

BMJ (Clinical research ed.). 1994;308(6923):260-2

Davies AE, Robertson MJ

Pulmonary oedema after the administration of intravenous salbutamol and ergometrine. Case report.

British journal of obstetrics and gynaecology. 1980;87(6):539-41

Nimrod CA, Beresford P, Frais M, Belenkie I, Tyberg J, Fremit A, Smith E

Hemodynamic observations on pulmonary edema associated with a beta-mimetic agent. A report of two cases.

The Journal of reproductive medicine. 1984;29(5):341-4

Mabie WC, Pernoll ML, Witty JB, Biswas MK

Pulmonary edema induced by betamimetic drugs.

Southern medical journal. 1983;76(11):1354-60

Guernsey BG, Villarreal Y, Snyder MD, Gabert HA

Pulmonary edema associated with the use of betamimetic agents in preterm labor.

American journal of hospital pharmacy. 1981;38(12):1942-8

Turner E, Rathgeber J, Kittel E, Grospietsch G, Braun U

[Fenoterol (Partusisten)-associated lung edema. A case report].

Der Anaesthesist. 1986;35(4):258-60

Russi EW, Spaetling L, Gmür J, Schneider H

High permeability pulmonary edema (ARDS) during tocolytic therapy--a case report.

Journal of perinatal medicine. 1988;16(1):45-9

Milos M, Aberle DR, Parkinson BT, Batra P, Brown K

Maternal pulmonary edema complicating beta-adrenergic therapy of preterm labor.

AJR. American journal of roentgenology. 1988;151(5):917-8

Pisani RJ, Rosenow EC 3rd

Pulmonary edema associated with tocolytic therapy.

Annals of internal medicine. 1989;110(9):714-8