The Drug-Induced Cardiotoxicity Website and App

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XXIV - Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

Pneumoconiosis (silicosis, talcosis...)

Last update 11/09/2026

(Fr: pneumoconiose-talcose). Mineral dust-induced lung disease. Mainly due to exposure to drugs (mostly abused) containing silica or talc. Not unlike occupational silicosis, large airway involvement remains a possibility (PMID 18583512)

Causative drugs

2

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

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