The Drug-Induced Cardiotoxicity Website and App

XXXVIII.q

XXXVIII - Miscellaneous - Varia

Myopathy-Myositis-Polymyositis (see also under Xba)

Last update 26/02/2019

Including acute myositis, rhabdomyolysis, a mimic of autoimmune anti-Jo1-positive polymyositis/dermato-polymyositis and necrotizing autoimmune myopathy. Respiratory muscles can be involved (PMID 12904161): see specifically under IXac

Causative drugs

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Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

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