XXVIII - Large airway involvement including UAO
Last update 17/06/2026
See also under VIIIa. Typically acute. May be due to edema, hematoma or rigidity. Increased tongue volume can cause serious breathing difficulties by obstructing the air passage and compressing the soft palate. Asphyxia may ensue. Speedy control of the airway is essential
Frequency - Incidence
Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
