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The Drug-Induced Cardiotoxicity Website and App

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

VI.a

Cardiomyopathy (acute, subacute, chronic)

Publications

Chapman L, Khalifa I, Sheriff N, Colwell N

Amphetamine-induced cardiomyopathy complicated by embolic stroke: a case report.

European heart journal. Case reports. 2022;6(2):ytac044

O'Neill ME, Arnolda LF, Coles DM, Nikolic G

Acute amphetamine cardiomyopathy in a drug addict.

Clinical cardiology. 1983;6(4):189-91