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The Drug-Induced Cardiotoxicity Website and App

XXXII.i

XXXII - Esophageal pathology

Pharmacobezoar

Last update 17/06/2026

Consist in the accumulation of coalescent tablets causing an aggregate in the digestive or respiratory tract (esopagus (compressing the airway), stomach, bowel, or trachea). May be visualized on plain chest films or CT as an electron-dense lumenal mass. May necessitate endoscopic fragmentation and removal to avoid mechanical complications and persistent drug exposure and/death. May follow a suicide attempt. PMID 1416337, 14767738, 15012180, 8590522

Causative drugs

1

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic