The Drug-Induced Cardiotoxicity Website and App

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XXII.b

ARDS - Acute lung injury

Publications

Dʼelia T, Ghio L

Acute respiratory distress syndrome after airway anesthesia with lidocaine.

Journal of bronchology & interventional pulmonology. 2010;17(3):245-7

Sutter M, Pfenninger J

[Adult respiratory distress syndrome (ARDS) after poisoning by local anesthetics].

Schweizerische medizinische Wochenschrift. 1982;112(47):1710-3

Howard JJ, Mohsenifar Z, Simons SM

Adult respiratory distress syndrome following administration of lidocaine.

Chest. 1982;81(5):644-5

Promisloff RA, DuPont DC

Death from ARDS and cardiovascular collapse following lidocaine administration.

Chest. 1983;83(3):585