The Drug-Induced Cardiotoxicity Website and App
Frequency - Incidence
Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
ARDS - Acute lung injury
Publications
Acute respiratory distress syndrome mimickers lacking common risk factors of the Berlin definition.
Intensive care medicine. 2016;42(2):164-72
Antithymocyte globulin-induced acute respiratory distress syndrome after renal transplantation: a case report.
Chinese medical journal. 2012;125(9):1664-6
Antithymocyte globulin-induced acute lung injury during transplantation for aplastic anemia.
Journal of pediatric hematology/oncology. 2011;33(2):150-2
Acute respiratory distress syndrome after kidney transplantation: epidemiology, risk factors, and outcomes.
Critical care medicine. 2003;31(5):1325-30
Transient pulmonary infiltrates during treatment with anti-thymocyte globulin.
Respiration; international review of thoracic diseases. 1999;66(3):279-82
Adult respiratory distress syndrome related to antilymphocyte globulin therapy.
Chest. 1987;91(4):619-20
ARDS following equine ATG therapy.
Chest. 1987;92(3):578