The Drug-Induced Cardiotoxicity Website and App

Cyanoacrylate (N-butyl-2-cyanoacrylate-Histoacryl)

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XIII.e

Cyanoacrylate pulmonary embolism

Publications

Pietrasik A, Gąsecka A, Chojecka D, Pytlos J, Rymuza B, Główczyńska R, Banaszkiewicz M, Darocha S, Kurzyna M

Iatrogenic pulmonary embolism with cyanoacrylate - to remove, or to leave?

Kardiologia polska. 2021;79(6):706-707

Frassei JDS, Franco CS, Brambilla VR, Loureiro BMC, Kiebert CDS, Fonseca EKUN, Ando SM, Sawamura MVY

Cyanoacrylate pulmonary embolism after endoscopic sclerotherapy of gastric varices.

Einstein (Sao Paulo, Brazil). 2021;19:eAI5778