The Drug-Induced Cardiotoxicity Website and App

Mesalazine-Mesalamine-5-aminosalicylic acid (5ASA)

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XXIV.t

ILD with a granulomatous component

Publications

Fayaz M, Sultan A, Nawaz M, Sultan N

Mesalazine-induced eosinophilic variant of Wegener's granulomatosis in an ulcerative colitis patient.

Journal of Ayub Medical College, Abbottabad : JAMC. 2009;21(4):171-3

Kohli R, Melin-Aldana H, Sentongo TA

Mesalamine-induced pneumonitis during therapy for chronic inflammatory bowel disease: a pediatric case report.

Journal of pediatric gastroenterology and nutrition. 2005;41(4):479-82

Foster RA, Zander DS, Mergo PJ, Valentine JF

Mesalamine-related lung disease: clinical, radiographic, and pathologic manifestations.

Inflammatory bowel diseases. 2003;9(5):308-15