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The Drug-Induced Cardiotoxicity Website and App

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XXXVIII.e

Sniffing death - Death from inhalation of compound

Publications

Piersanti V, Napoletano G, David MC, Umani Ronchi F, Marinelli E, De Paola L, Zaami S

Sudden death due to butane abuse - An overview.

Journal of forensic and legal medicine. 2024;103:102662

Durão C, Pedrosa F, Dinis-Oliveira RJ

Suicide by inhalation of butane gas through a homemade adaptation of a continuous positive airway pressure (CPAP) face mask.

Forensic science, medicine, and pathology. 2020;16(4):732-734

Alunni V, Gaillard Y, Castier F, Piercecchi-Marti MD, Quatrehomme G

Death From Butane Inhalation Abuse in Teenagers: Two New Case Studies and Review of the Literature.

Journal of forensic sciences. 2018;63(1):330-335