The Drug-Induced Cardiotoxicity Website and App

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

III.c

Coronary vasospasm - Vasospastic angina

Publications

Kolos IP, Chernyshova VA, Konstantinova EV, Gilyarov MY

[Capecitabine and vasospastic angina: a clinical case].

Kardiologiia. 2022;62(2):36-41

Nykamp MJ, Marks L, Kerby PW, Cristancho P

Negative Pressure Pulmonary Edema After Electroconvulsive Therapy.

The journal of ECT. 2021;37(4):220-221

Henry D, Rudzik F, Butts A, Mathew A

Capecitabine-Induced Coronary Vasospasm.

Case reports in oncology. 2016;9(3):629-632