The Drug-Induced Cardiotoxicity Website and App
Frequency - Incidence
Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Intracardiac bone cement embolism
Publications
Diagnosis of bone cement implantation syndrome using point of care ultrasound examination.
Annals of cardiac anaesthesia. 2021;24(3):372-374
Fatal cardiac perforation and pulmonary embolism of leaked cement after percutaneous vertebroplasty.
Journal of forensic and legal medicine. 2019;63:48-51
Intracardiac bone cement embolism as a complication of vertebroplasty: management strategy.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2017;26(12):3199-3205