The Drug-Induced Cardiotoxicity Website and App

Waterproofing agents/sprays - Household cleansing agents and aerosols

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XXIV.j

Progression, acceleration or exacerbation of preexisting ILD/fibrosis

Publications

Futatsuya C, Minato H, Okayama Y, Katayanagi K, Kurumaya H, Yuasa M, Nishi K

An Autopsy Case of Idiopathic Pleuroparenchymal Fibroelastosis with Left Vocal Cord Paralysis and a Rapid Deterioration without an Acute Exacerbation.

Internal medicine (Tokyo, Japan). 2020;59(12):1541-1547

Bennett D, Bargagli E, Refini RM, Pieroni MG, Fossi A, Romeo R, Volterrani L, Mazzei MA, Rottoli P

Acute exacerbation of idiopathic pulmonary fibrosis after inhalation of a water repellent.

International journal of occupational medicine and environmental health. 2015;28(4):775-9