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The Drug-Induced Cardiotoxicity Website and App

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XXXVIII.m

Metabolic acidosis (incl. lactic acidosis/-gap). May cause hyperpnea/dyspnea

Publications

Nekoukar Z, Zakariaei Z, Taghizadeh F, Musavi F, Banimostafavi ES, Sharifpour A, Ebrahim Ghuchi N, Fakhar M, Tabaripour R, Safanavaei S

Methanol poisoning as a new world challenge: A review.

Annals of medicine and surgery (2012). 2021;66:102445

Kraut JA, Mullins ME

Toxic Alcohols.

The New England journal of medicine. 2018;378(3):270-280

Vossen LM, van Dongen CM, Schoutteten MK, de Wit HA, de Leeuw PW

Survival after intoxication with inhaled methanol.

The Netherlands journal of medicine. 2015;73(6):304

Loza R, Rodriguez D

A case of methanol poisoning in a child.

Case reports in nephrology. 2014;2014:652129