The Drug-Induced Cardiotoxicity Website and App

Pacemaker leads - Implantable cardiac devices

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XIV.e

Hemothorax - Serosanguineous pleural effusion

Publications

Gianni C, Canby RC, Anannab A, Della Rocca DG, Natale A, Al-Ahmad A

The Subtle Journey of a Right Atrial Lead: Hemopneumothorax Due to Subacute Pacemaker Lead Perforation.

JACC. Case reports. 2020;2(6):902-906

Liang JJ, Killu AM, Osborn MJ, Jaffe AS

Pacemaker lead perforation causing hemopericardium eight years after implantation.

Indian heart journal. 2013;65(3):331-3