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The Drug-Induced Cardiotoxicity Website and App

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XXIV.a

Pneumonitis (interstitial lung disease/ILD)

Publications

Sumi T, Terai K, Suzuki K, Koshino Y, Ikeda T, Watanabe H, Yamada Y, Chiba H

Minocycline-induced Acute Fibrinous and Organizing Pneumonia.

American journal of respiratory and critical care medicine. 2023;208(12):e47-e48

Barbagelata López C, Otero Palleiro MM, Seoane González B, Sánchez Vidal E

[Minocycline-induced hypersensitivity pneumonitis].

Medicina clinica. 2007;128(2):79

Rikken NE, Klinkhamer PJ, Haak HR

Interstitial pneumonia and hepatitis caused by minocycline.

The Netherlands journal of medicine. 2004;62(2):62-4