The Drug-Induced Cardiotoxicity Website and App

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XXIV.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

Imaging features e.g.: PMID : 23996619

Publications

Poschenrieder F, Schulz C, Hamer OW

[Eosinophilic pneumonia toxicity induced by Dapsone].

RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. 2014;186(2):178-9

Adar T, Tayer-Shifman O, Mizrahi M, Tavdi S, Barak O, Shalit M

Dapsone induced eosinophilic pneumonia.

European annals of allergy and clinical immunology. 2012;44(3):144-6

Kaur J, Khandpur S, Seith A, Khanna N

Dapsone-induced eosinophilic pneumonitis in a leprosy patient.

Indian journal of leprosy. 2005;77(3):267-71

Arunthathi S, Raju S

Dapsone induced pulmonary eosinophilia without cutaneous allergic manifestations--an unusual encounter--a case report.

Acta leprologica. 1998;11(1):3-5

Jaffuel D, Lebel B, Hillaire-Buys D, Pene J, Godard P, Michel FB, Blayac JP, Bousquet J, Demolyi P

Eosinophilic pneumonia induced by dapsone.

BMJ (Clinical research ed.). 1998;317(7152):181

Janier M, Guillevin L, Badillet G

Pulmonary eosinophilia associated with dapsone.

Lancet (London, England). 1994;343(8901):860-1