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The Drug-Induced Cardiotoxicity Website and App

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XXXVIII.d

Death following exposure or poisoning

From acute asthma attack or from cardias disturbances in poisoning

Publications

Spitz DJ

An unusual death in an asthmatic patient.

The American journal of forensic medicine and pathology. 2003;24(3):271-2

Benatar SR, Opie LH

Sudden death in asthmatics receiving beta-blockers.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 1982;62(10):308-9

Auzépy P, Boukara N, Richard C, Giudicelli JF

[Acute poisoning caused by beta blockers in the adult. Apropos of 7 cases].

Annales de cardiologie et d'angeiologie. 1983;32(4):253-8