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The Drug-Induced Cardiotoxicity Website and App

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XIII.c

Cement embolism

Publications

Papiamonis NE, Matrella E, Blevrakis EG, Kouroumalis EA

Acute pulmonary embolism following N-butyl-cyanoacrylate endoscopic injection sclerotherapy.

Annals of gastroenterology. 2012;25(3):261

Kazi S, Spanger M, Lubel J

Education and imaging: gastrointestinal: pulmonary embolism of cyanoacrylate glue following endoscopic injection of gastric varices.

Journal of gastroenterology and hepatology. 2012;27(12):1874

Favrolt N, Bonniaud P, Cercueil JP, Logerot S, Foucher P, Camus C, Camus P

[Pulmonary embolism by cyanoacrylate following embolisation of an arteriovenous malformation].

Revue des maladies respiratoires. 2009;26(1):74-7

Alexander S, Korman MG, Sievert W

Cyanoacrylate in the treatment of gastric varices complicated by multiple pulmonary emboli.

Internal medicine journal. 2006;36(7):462-5

van Beek AP, van Erpecum KJ

Fatal N-butyl-2-cyanoacrylate pulmonary embolism after sclerotherapy for variceal bleeding.

Endoscopy. 2005;37(7):687

Rickman OB, Utz JP, Aughenbaugh GL, Gostout CJ

Pulmonary embolization of 2-octyl cyanoacrylate after endoscopic injection therapy for gastric variceal bleeding.

Mayo Clinic proceedings. 2004;79(11):1455-8

Hwang SS, Kim HH, Park SH, Kim SE, Jung JI, Ahn BY, Kim SH, Chung SK, Park YH, Choi KH

N-butyl-2-cyanoacrylate pulmonary embolism after endoscopic injection sclerotherapy for gastric variceal bleeding.

Journal of computer assisted tomography. 2001;25(1):16-22