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The Drug-Induced Cardiotoxicity Website and App

Frequency - Incidence

Incidence of cardiac adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for cardiac adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XVI.e

Alveolar hemorrhage (AH), diffuse AH (DAH)

Publications

Toquet S, Cousson J, Choiselle N, Gozalo C, Giusti D, Bani-Sadr F, N'Guyen Y

Alveolar hemorrhage due to marijuana smoking using water pipe made with plastic bottle: case report and narrative review of the literature.

Inhalation toxicology. 2021;33(5):168-176

Bucchino L, Monzani A, Fracon S, Genoni G, Cena T, Bellone S

Cannabis-Related Diffuse Alveolar Hemorrhage in a 16-Year-Old Patient: A Case Report.

Frontiers in pediatrics. 2019;7:468

Moatemri Z, Zaibi H, Dabboussi S, Mhamedi S, Aichaouia C, Khadhraoui M, Cheikh R

[Alveolar haemorrhage following a cannabis water pipe].

Revue de pneumologie clinique. 2016;72(5):316-319

Hashmi HR, Duncalf R, Khaja M

A Case Report of Cannabis Induced Hemoptysis.

Medicine. 2016;95(13):e3232

de Prost N, Parrot A, Cuquemelle E, Picard C, Antoine M, Fleury-Feith J, Mayaud C, Boffa JJ, Fartoukh M, Cadranel J

Diffuse alveolar hemorrhage in immunocompetent patients: etiologies and prognosis revisited.

Respiratory medicine. 2012;106(7):1021-32

Grassin F, André M, Rallec B, Combes E, Vinsonneau U, Paleiron N

[Fatal alveolar haemorrhage following a "bang" of cannabis].

Revue des maladies respiratoires. 2011;28(7):919-23

La Rosa FG, Clarke SH, Lefkowitz JB

Brodifacoum intoxication with marijuana smoking.

Archives of pathology & laboratory medicine. 1997;121(1):67-9